Preclinical Safety Testing Program for Pharma/Biotech

Preclinical Drug Safety Studies and Programs

Toxikon's "Preclinical Safety Testing Program for Pharma/Biotech" includes a wide range of pharmacokinetic, acute toxicity, repeat dose toxicity, genotoxicity and developmental and reproductive toxicology studies. (See list below).

Click here for more information on Toxikon's study designs.

To access Toxikon's Pharmaceutical / API Test Requisition Form, click here

For Test or Control Material Fact Sheet, click here

For more specifics, or for information on Toxikon's Custom capabilities, click here or fill out the form to the right. 

 Pharmacokinetic Studies 

Single Dose PK Study in Rats/Mice     

Single Dose PK Study in Non-Naïve Beagle Dogs—Parallel Session            

Single Dose PK Study in Non-Naïve Beagle Dogs —4 Crossover Sessions

Repeat Dose PK Study in Non-Naïve Beagle Dogs  

Single Dose PK Study in Non-Human Primates

Repeat Dose PK Study in Non-Human Primates

Acute Toxicity—Sample Designs             

Single-Dose Toxicity Study in Rats/Mice, Dogs (Beagle), and Non-Human Primates

MTD Determination with Repeat Dose Range-Finding in Rats/Mice, Dogs (Beagle), and Non-Human Primates   

Repeat Dose Toxicity Studies—GLP   

14-Day Repeat Dose Toxicity Study in Rats/Mice, Dogs (Beagle), and Non-Human Primates                

28-Day Repeat Dose Toxicity Study in Rats/Mice, Dogs (Beagle), and Non-Human Primates                

90-Day Repeat Dose Toxicity Study in Rats/Mice          

10-Day Repeat Dose Toxicity Study in Dogs (Beagle)

Carcinogenicity

Genotoxicity Studies     

Ames Reverse mutation assay in S. typhimurium and E.coli                         

Chromosomal Aberration Assay with CHO cells                 

Chromosomal Aberration Assay with Human Lymphocytes                         

Rodent Bone Marrow Micronucleus Test                             

Dose-Verification Study      

COMET Assay

Developmental & Reproductive Toxicology         

Embryo Fetal Development Study in Rats/Mice—Dose Range Finding

Embryo Fetal Development Study in Rats/Mice—Definitive    

Embryo Fetal Development Study in Rabbits—Dose Range Finding          

Embryo Fetal Development Study in Rabbits—Definitive              

Fertility Study in Rats/Mice     

Pre and Post Natal Development Study in Rats/Mice

 

To request medical device development tests, click the Devices icon.

  

 

                    

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Preclinical Research and Development Services | Preclinical Trial and Testing Solutions
Preclinical Trial, Pre Clinical Trials, Preclinical Development, Preclinical Research, Preclinical Research Services, Preclinical Services, Preclinical Testing, Preclinical Tests
Toxikon is a contract research organization providing preclinical research and development services for pharma, biotech and medical device sectors. Our preclinical trial and testing solutions include toxicology, pharmacokinetics, bioanalytical, and microbiology/virology.