General Toxicology

The objective of this testing program is to provide accurate and reliable data that is utilized in assessments relating to human and environmental exposure.

Currently, Toxikon offers complete acute, subchronic, and chronic testing programs, which include the following species:

• Cats
• Dogs
• Goats
• Guinea pigs
• Hamsters
• Mice
• Rabbits
• Rats
• Swine
• Sheep
• NHPs

Routes of Administration

• Oral (gavage, diet, capsule)
• Parenteral (intravenous, subcutaneous, intramuscular, and intraperitoneal)
• Buccal
• Dermal and intradermal
• Intranasal
• Intravaginal
• Ocular
• Rectal

Studies

• 1-3 month subchronic
• 2 year carcinogenicity
• 6, 9, and 12 - month chronic
• Acute
• Assessments in carcinogenicity studies where required
• In utero exposure
• Neurobehavioral
• Surgical models
• Wound healing

Toxikon employs qualified and experienced staff and offers comprehensive In Vivo testing programs. The state-of-the-art facilities offer laboratory support in the areas of diet preparation and analytical chemistry, necropsy, surgery, tissue processing, and histopathologic diagnostics.

The addition of data acquisition system Provantis™ allows better control of study management and data collection and analyses for studies involving clinical pathology, necropsy and histopathology.