Aninal Models of Disease | Models and Mechanisms | Surgical Models | Wound Healing, Xenograft Tumor Models

Animal / Disease Models

Cancer (Xenograft Tumor Models)

• Prostate cancer: LNcap, DU145, PC-3
• Lung Cancer:NCI-H460, NCI-H69, HOP-92
• Breast cancer: MDA-MB-468, MCF-7, MCF-7 (MDR+),  MDA-MB-231
• Liver Cancer: PLC-5, Hep3B
• Colon: HT29, COLO-205
• Pancreatic Cancer:PANC-1
• Brain: US7MG
• Promyelocytic: HL-60, THP-1
• B cell lymphoma: Ramos, RaJI

*These are the models we have validated and using for our clients. However we can develop any other type of tumor models.

Inflammatory Diseases

Rheumatoid Arthritis (RA)

• Collagen Induced Arthritis (CIA ) in Mice,  Rats
• Adjuvant Induced Arthritis (AIA) in Rats
• Carageenan induced Arthritis in Rats

Inflammatory Bowel Diseases (IBD)

• DSS- induced Colitis in Mice and Rats
• Oxazolone-induced colitis in mice
• DNBS/TNBS induced colitis in Rats
• Acetic Acid induced colitis in Rats

Multiple Sclerosis

• Acute Experimental allergic Encephalomyelitis (EAE) in Rats, Mice using MBP
• Chronic Experimental allergic Encephalomyelitis (EAE) in Mice, using MOG.
• Relapsing Experimental allergic Encephalomyelitis (EAE) in Mice, using PLP

 Atopic Dermatitis

•  Mouse Atopic Dermatitis using NC/Nga mouse

Allergic Contact Dermatitis (ACD)

• DNCB induced ACD in Mini pigs, Guinea pigs
• DNFB induced ACD in mice

Lung Disease

• LPS induced Lung inflammation in mice

Wound Healing Models

• Regular Mice
• Nude Mice
• Rats
• Mini pigs

 Experimental Autoimmune Uveitis (EAU)

• EAU in Mice
• EAU in Rats

Gastric Ulcers

• Acute gastric ulcer in Rats
• Acute gastric ulcer in Mice

Diabetes and Obesity Models

• Ob/Ob Mouse model
• Zucker Diabetic Fatty Rat model
• Streptozotocin induced diabetes in rat and mouse
• Spontaneous Hypertensive Rat model
• Pancreatectomy-Induced Diabetes (various species)

Ocular Models

• Dry eye
• EAU Uveitis
• Glaucoma / IOP
• Corneal NV / AMD
• Chorodial NV / AMD (Subretinal NV)
• Retinal NV / AMD, DR

Surgical Models

• Wound Healing
• Orthopedic
• Anastomosis
•  Disease Model Development