Custom Synthesis Services | Dose Formulation Analysis | Custom Chemical Synthesis

Custom Synthesis

Toxikon’s Drug Discovery Group (DDG) and its cost-effective operations provides partners and clients worldwide access to comprehensive drug discovery and development support to our clients. Our scientists and study directors, along with our business partners, have the experience and infrastructure available to your projects so that reasonable timelines are met. Based on your needs, our Drug Discovery Group forms highly responsive teams led by experienced researchers to deliver a customized package of services.

Our medicinal chemistry team offers the following services:

• Design and synthesis of small molecules and analogs for lead generation and lead optimization;
• Preparation of building blocks, scaffolds and intermediate compounds;
• Custom synthesis of lead compounds from milligrams to large scale;
• Synthesis of reference compounds and metabolites. 

Formulation

 In support of product development, formulations are needed to preserve the stability and to enhance the effectiveness of pharmaceuticals. Toxikon provides analytical chemistry capabilities to test raw materials, APIs, and excipients used in formulation as well as stability studies and container/material compatibility to evaluate the impact of material compositions on the formulation. In addition, bioavailability, ADME, PK, DMPK, and efficacy studies can also be performed in support of formulation development.

 Our services in this category include:

• Analytical
• Pharmacology
• Toxicology